Dynamics of chromatin architecture during cell transformation.
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We use Chromatin Interaction Analysis by Paired End Tag Sequencing (ChIA-PET) to map changes in higher order chromatin structure that facilitate cell transformation. 

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Topological properties of chromatin organization
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We employ machine learning and principles of network topology to study 3D chromatin organization by leveraging one dimensional genetic and epigenomic features.

​Kai et al. Predicting CTCF-mediated chromatin interactions by integrating genomic and epigenomic features.
​Nature Communications. October 2018

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ἀγεωμέτρητος μηδεὶς εἰσίτω 
let no one ignorant of geometry enter
Plato's Academy (Athens, Greece, ca. 387 BC)

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